February 7, 2010 – 11:23 am
Michael Longaker MD, Professor of Surgery from Stanford University, has said:
- “This technique is not only safer, it’s relatively simple …”
- “It will be a relatively straightforward process for labs around the world to begin using this technique.”
- “We are moving toward clinically applicable regenerative medicine.”
More from a Release dated February 7, sourced from Stanford University Medical Center:
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Posted in Reprogramming cells
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Tagged adult cells, cardiac gene therapy, heart disease, human heart, human heart disease, human regenerative medicine, induce pluripotency, induced pluripotent stem cells, minicircles, molecular biology, non-viral reprogramming, pluripotent cells, pluripotent stem cells, regenerative, relative safety, specialized cell types, stanford researchers, stanford scientists, stanford university medical center, stanford university school, stanford university school of medicine, stem cell rejuvenation, stem cells, university medical center
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February 6, 2010 – 8:43 am
Martin Hetzer PhD, Hearst Endowment Associate Professor from Salk Institute’s Molecular and Cell Biology Laboratory has said:
- “Nuclear pores are not only transport channels but play a role in the organization of the genome and a very direct role in gene expression …”
- “NPC components, called nucleoporins, are also present in the nuclear interior and bind to certain genes, which puts them in a new class of gene regulators.”
More from a Release dated February 4, sourced from Salk Institute:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged active genes, bona fide transcription regulator, cause of leukemia, cell biology laboratory, cell differentiation, cell nucleus, communication channels, constituent proteins, double duty, gene expression, genome, longstanding mystery, molecular and cell biology, multicellular organisms, new insights, nuclear membrane, nuclear pore complexes, nuclear pores, nucleoporins, overexpressed, polytene, polytene chromosome, polytenized, pore protein, regulators for developmental genes, regulatory function, salk institute for biological studies, tissue development, transcription factors, translocation causes
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February 3, 2010 – 9:50 pm
Professor Rick Wetsel PhD, from the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas, Houston, Texas, has indicated … “that an experimental treatment involving transplantable lung cells was associated with improved outcomes in tests on mice with acute lung injury.”
Mice receiving the transplantable lung cells lived longer, sustained less scarring in their lungs and had normal amounts of oxygen in their blood, said
More from a Release dated February 2, sourced from University of Texas Health Science Center at Houston:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged acute lung injury, brown foundation, embryonic stem cells, human diseases, human embryonic stem cells, lung cells, memorial hermann hospital, molecular medicine, mortality and morbidity, novel approach, progenitor cells, respiratory diseases, texas health science, texas health science center, texas medical school, university of texas health science center, university of texas houston
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February 2, 2010 – 3:16 am
Researchers from the Karolinska Institutet in Sweden have indicated “… that stem cells transplanted into damaged or threatened nerve tissue quickly establish direct channels, called gap junctions, to the nerve cells. ”
More from a Release dated February 1, sourced from Karolinska Institutet:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged brain damage, brain injuries, brain tissue, cross talk, direct contact, gap, gap junctions, growth factors, international research groups, karolinska institutet, medical university, molecular signals, nerve cells, nerve tissue, neurodegenerative diseases, rodent models, stem cells, swedish medical
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January 30, 2010 – 12:16 pm
Linheng Li PhD, from the University of Kansas School of Medicine, in Kansas City, Kansas; and Hans Clevers MD PhD, from the Hubrecht Institute in Utrecht, Netherlands; have indicated … ‘a model of mammalian adult stem cell regulation that may explain how the coexistence of two disparate stem cell states regulates both stem cell maintenance and simultaneously supports rapid tissue regeneration. ‘
More from a Release dated January 29, sourced from Stowers Institute for Medical Research:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged Adult stem cells, cell populations, cell states, coexistence, functional roles, hair follicle, kansas city kansas, kansas city mo, netherlands, neural system, novel theory, physiological tissue, tissue regeneration, university of kansas, utrecht
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January 28, 2010 – 9:35 am
Nicholas Zavazava MD PhD, from the University of Iowa, has said:
- “Our study shows that transplanted bone marrow cells fuse not only with bone marrow cells of the recipient, but with non-hematopoietic cells, suggesting that if we can understand the process of cell fusion better, we may be able to target certain organ injuries with the patient’s own bone marrow cells and repair the tissues …”
More from a Release dated January 28, sourced from Federation of American Societies for Experimental Biology:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged bone marrow cells, cell fusion, different types of cells, embryonic stem cell, embryonic stem cells, faseb, federation of american societies for experimental biology, hematopoietic cells, hybrid cells, hybrids, immune rejection, iowa researcher, mouse strains, new strategy, stem cell transplants, university of iowa
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January 27, 2010 – 10:47 pm
Yingqun Huang MD, Assistant Professor from the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine, has said:
- “We found that stopping the expression of two genes–Lin28 and Oct4–reduces ovarian cancer cell growth and survival …”.
- “This recurrence and drug resistance may be due to the presence of CSCs within the tumors that have the capacity to reproduce and to differentiate into non-CSC tumor cells that repopulate the tumor mass …”
- “Eliminating these CSCs may be key to successful treatments.”
More from a Release dated January 27, sourced from Yale University:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged cancer cell growth, cell proteins, drug resistance, embryonic stem cells, human embryonic stem cells, moniker, nonspecific symptoms, obstetrics gynecology, ovarian cancer, recurrence, reproductive sciences, stopping the expression, tumor cells, tumor mass, yale cancer center, yale school of medicine, yale university
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January 26, 2010 – 12:29 pm
Researchers from the Boston University School of Medicine (BUSM) have indicated that “… the TGFβ-Smad signaling pathway, which is over activated in late-stage cancers, is responsible for the “epigenetic memory” that maintains unique patterns of regulatory DNA hypermethylation causing silencing of critical genes that facilitate breast cancer progression.”
More from a Release dated January 25, sourced from Boston University Medical Center:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged boston researchers, boston university medical center, boston university school, boston university school of medicine, breast cancer, busm, cancer cells, cancer progression, cancer research, critical genes, demethylation, direct perturbation, dna binding activity, dna sequence, genetic blueprint, promoter dna, regulatory dna, smad, smad signaling pathway, tumor cells
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January 24, 2010 – 11:05 pm
- “Stem cells, which are clonogenic cells with self-renewal and multilineage differentiation properties, have the potential to replace or repair damaged tissue.”1
Researchers from StemCells Inc, Sunnyvale, California; Laboratory of Genetics, the Salk Institute, La Jolla, California; and Departments of Pathology and Developmental Biology, Stanford University, Stanford, California; have presented an article titled: “Direct isolation of human central nervous system stem cells.”
The researchers from Sunnyvale, La Jolla, and Stanford have also noted:
- “… directly isolated clonogenic human central nervous system stem cells (hCNS-SC) from fresh human fetal brain tissue, using antibodies to cell surface markers and fluorescence-activated cell sorting.”
- “These hCNS-SC are phenotypically 5F3 (CD133)(+), 5E12(+), CD34(-), CD45(-), and CD24(-/lo).”
- “Single CD133(+) CD34(-) CD45(-) sorted cells initiated neurosphere cultures, and the progeny of clonogenic cells could differentiate into both neurons and glial cells.”
- “Single cells from neurosphere cultures initiated from CD133(+) CD34(-) CD45(-) cells were again replated as single cells and were able to reestablish neurosphere cultures, demonstrating the self-renewal potential of this highly enriched population.”
- “Upon transplantation into brains of immunodeficient neonatal mice, the sorted/expanded hCNS-SC showed potent engraftment, proliferation, migration, and neural differentiation.”
(1) Uchida N, Buck DW, He D, Reitsma MJ, Masek M, Phan TV, Tsukamoto AS, Gage FH, Weissman IL: Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14720-5.
By info@sujanani.com
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Posted in Stem cell research
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Tagged california laboratory, cell surface markers, central nervous system, central nervous system stem cells, developmental biology, direct isonaltion, fetal brain tissue, gage fh, glial cells, human cns stem cells, neural differentiation, salk institute la jolla, self-renewal, stanford california, stanford university stanford, stem cells, sunnyvale california
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January 22, 2010 – 3:03 pm
Researchers from the Royal Melbourne Hospital and the University of Melbourne in Victoria, Australia have reported “… cells that cause a common type of childhood leukaemia – T cell Acute Lymphoblastic Leukaemia (T-ALL). Targeting of these cells may lead to improved treatments for this disease and help prevent relapse.”
More from a Release dated January 21, sourced from University of Melbourne:
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By info@sujanani.com
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Posted in Stem cell research
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Tagged animal models, bone marrow, childhood leukaemia, childhood leukemia, irradiation treatment, long periods, lymphoblastic leukaemia, melbourne scientists, research laboratories, royal melbourne hospital, stem cells, thymus, university of melbourne, victoria australia
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